Class: Intercurrent Event (IntercurrentEvent)

An event(s) occurring after treatment initiation that affects either the interpretation or the existence of the measurements associated with the clinical question of interest. (ICH E9 Addendum on Estimands)

URI: https://example.org/usdm/v4/linkml/IntercurrentEvent

 classDiagram
    class IntercurrentEvent
    click IntercurrentEvent href "../../classes/IntercurrentEvent/"
      SyntaxTemplate <|-- IntercurrentEvent
        click SyntaxTemplate href "../../classes/SyntaxTemplate/"

      IntercurrentEvent : description

      IntercurrentEvent : dictionaryId





        IntercurrentEvent --> "0..1" SyntaxTemplateDictionary : dictionaryId
        click SyntaxTemplateDictionary href "../../classes/SyntaxTemplateDictionary/"



      IntercurrentEvent : extensionAttributes





        IntercurrentEvent --> "*" ExtensionAttribute : extensionAttributes
        click ExtensionAttribute href "../../classes/ExtensionAttribute/"



      IntercurrentEvent : id

      IntercurrentEvent : label

      IntercurrentEvent : name

      IntercurrentEvent : notes





        IntercurrentEvent --> "*" CommentAnnotation : notes
        click CommentAnnotation href "../../classes/CommentAnnotation/"



      IntercurrentEvent : strategy

      IntercurrentEvent : text

Inheritance

Class Properties

Property Value
Class URI usdm:IntercurrentEvent

Slots

Name Cardinality and Range Description Inheritance
strategy 1
string		 A textual description of the planned strategy to manage and/or mitigate intercurrent events. direct
extensionAttributes *
ExtensionAttribute		 direct
id 1
string		 SyntaxTemplate
name 1
string		 The literal identifier (i.e., distinctive designation) of the characteristic. SyntaxTemplate
label 0..1
string		 The short descriptive designation for the characteristic. SyntaxTemplate
description 0..1
string		 A narrative representation of the characteristic. SyntaxTemplate
text 1
string		 An instance of structured text that represents the characteristic. SyntaxTemplate
notes *
CommentAnnotation		 A brief written record relevant to the characteristic. SyntaxTemplate
dictionaryId 0..1
SyntaxTemplateDictionary		 A USDM relationship between the Characteristic and SyntaxTemplateDictionary classes which provides the set of dictionary entries related to characteristics. SyntaxTemplate

Usages

used by used in type used
Estimand intercurrentEvents range IntercurrentEvent

Identifier and Mapping Information

Schema Source

  • from schema: https://example.org/usdm/v4/linkml

Mappings

Mapping Type Mapped Value
self https://example.org/usdm/v4/linkml/IntercurrentEvent
native https://example.org/usdm/v4/linkml/IntercurrentEvent
exact ncit:C188815

LinkML Source

Direct

name: IntercurrentEvent
description: An event(s) occurring after treatment initiation that affects either
  the interpretation or the existence of the measurements associated with the clinical
  question of interest. (ICH E9 Addendum on Estimands)
title: Intercurrent Event
from_schema: https://example.org/usdm/v4/linkml
exact_mappings:
- ncit:C188815
rank: 1000
is_a: SyntaxTemplate
attributes:
  strategy:
    name: strategy
    description: A textual description of the planned strategy to manage and/or mitigate
      intercurrent events.
    title: Intercurrent Event Strategy
    from_schema: https://example.org/usdm/v4/linkml
    exact_mappings:
    - ncit:C188857
    rank: 1000
    domain_of:
    - IntercurrentEvent
    range: string
    required: true
  extensionAttributes:
    name: extensionAttributes
    from_schema: https://example.org/usdm/v4/linkml
    domain_of:
    - Abbreviation
    - Activity
    - Address
    - AdministrableProduct
    - AdministrableProductIdentifier
    - AdministrableProductProperty
    - Administration
    - AliasCode
    - AnalysisPopulation
    - AssignedPerson
    - BiomedicalConcept
    - BiomedicalConceptCategory
    - BiomedicalConceptProperty
    - BiomedicalConceptSurrogate
    - BiospecimenRetention
    - Characteristic
    - Code
    - CommentAnnotation
    - Condition
    - ConditionAssignment
    - DocumentContentReference
    - Duration
    - EligibilityCriterion
    - EligibilityCriterionItem
    - Encounter
    - Endpoint
    - Estimand
    - ExtensionAttribute
    - ExtensionClass
    - GeographicScope
    - GovernanceDate
    - Indication
    - Ingredient
    - IntercurrentEvent
    - InterventionalStudyDesign
    - Masking
    - MedicalDevice
    - MedicalDeviceIdentifier
    - NarrativeContent
    - NarrativeContentItem
    - Objective
    - ObservationalStudyDesign
    - Organization
    - ParameterMap
    - PersonName
    - Procedure
    - ProductOrganizationRole
    - Quantity
    - Range
    - ReferenceIdentifier
    - ResponseCode
    - ScheduleTimeline
    - ScheduleTimelineExit
    - ScheduledActivityInstance
    - ScheduledDecisionInstance
    - Strength
    - Study
    - StudyAmendment
    - StudyAmendmentImpact
    - StudyAmendmentReason
    - StudyArm
    - StudyCell
    - StudyChange
    - StudyCohort
    - StudyDefinitionDocument
    - StudyDefinitionDocumentVersion
    - StudyDesignPopulation
    - StudyElement
    - StudyEpoch
    - StudyIdentifier
    - StudyIntervention
    - StudyRole
    - StudySite
    - StudyTitle
    - StudyVersion
    - SubjectEnrollment
    - Substance
    - SyntaxTemplateDictionary
    - Timing
    - TransitionRule
    range: ExtensionAttribute
    required: false
    multivalued: true
    inlined: true
    inlined_as_list: true
class_uri: usdm:IntercurrentEvent

Induced

name: IntercurrentEvent
description: An event(s) occurring after treatment initiation that affects either
  the interpretation or the existence of the measurements associated with the clinical
  question of interest. (ICH E9 Addendum on Estimands)
title: Intercurrent Event
from_schema: https://example.org/usdm/v4/linkml
exact_mappings:
- ncit:C188815
rank: 1000
is_a: SyntaxTemplate
attributes:
  strategy:
    name: strategy
    description: A textual description of the planned strategy to manage and/or mitigate
      intercurrent events.
    title: Intercurrent Event Strategy
    from_schema: https://example.org/usdm/v4/linkml
    exact_mappings:
    - ncit:C188857
    rank: 1000
    alias: strategy
    owner: IntercurrentEvent
    domain_of:
    - IntercurrentEvent
    range: string
    required: true
  extensionAttributes:
    name: extensionAttributes
    from_schema: https://example.org/usdm/v4/linkml
    alias: extensionAttributes
    owner: IntercurrentEvent
    domain_of:
    - Abbreviation
    - Activity
    - Address
    - AdministrableProduct
    - AdministrableProductIdentifier
    - AdministrableProductProperty
    - Administration
    - AliasCode
    - AnalysisPopulation
    - AssignedPerson
    - BiomedicalConcept
    - BiomedicalConceptCategory
    - BiomedicalConceptProperty
    - BiomedicalConceptSurrogate
    - BiospecimenRetention
    - Characteristic
    - Code
    - CommentAnnotation
    - Condition
    - ConditionAssignment
    - DocumentContentReference
    - Duration
    - EligibilityCriterion
    - EligibilityCriterionItem
    - Encounter
    - Endpoint
    - Estimand
    - ExtensionAttribute
    - ExtensionClass
    - GeographicScope
    - GovernanceDate
    - Indication
    - Ingredient
    - IntercurrentEvent
    - InterventionalStudyDesign
    - Masking
    - MedicalDevice
    - MedicalDeviceIdentifier
    - NarrativeContent
    - NarrativeContentItem
    - Objective
    - ObservationalStudyDesign
    - Organization
    - ParameterMap
    - PersonName
    - Procedure
    - ProductOrganizationRole
    - Quantity
    - Range
    - ReferenceIdentifier
    - ResponseCode
    - ScheduleTimeline
    - ScheduleTimelineExit
    - ScheduledActivityInstance
    - ScheduledDecisionInstance
    - Strength
    - Study
    - StudyAmendment
    - StudyAmendmentImpact
    - StudyAmendmentReason
    - StudyArm
    - StudyCell
    - StudyChange
    - StudyCohort
    - StudyDefinitionDocument
    - StudyDefinitionDocumentVersion
    - StudyDesignPopulation
    - StudyElement
    - StudyEpoch
    - StudyIdentifier
    - StudyIntervention
    - StudyRole
    - StudySite
    - StudyTitle
    - StudyVersion
    - SubjectEnrollment
    - Substance
    - SyntaxTemplateDictionary
    - Timing
    - TransitionRule
    range: ExtensionAttribute
    required: false
    multivalued: true
    inlined: true
    inlined_as_list: true
  id:
    name: id
    from_schema: https://example.org/usdm/v4/linkml
    identifier: true
    alias: id
    owner: IntercurrentEvent
    domain_of:
    - Abbreviation
    - Activity
    - Address
    - AdministrableProduct
    - AdministrableProductProperty
    - Administration
    - AliasCode
    - AnalysisPopulation
    - AssignedPerson
    - BiomedicalConcept
    - BiomedicalConceptCategory
    - BiomedicalConceptProperty
    - BiomedicalConceptSurrogate
    - BiospecimenRetention
    - Code
    - CommentAnnotation
    - ConditionAssignment
    - DocumentContentReference
    - Duration
    - EligibilityCriterion
    - Encounter
    - Estimand
    - ExtensionAttribute
    - ExtensionClass
    - GeographicScope
    - GovernanceDate
    - Identifier
    - Indication
    - Ingredient
    - Masking
    - MedicalDevice
    - NarrativeContent
    - NarrativeContentItem
    - Organization
    - ParameterMap
    - PersonName
    - PopulationDefinition
    - Procedure
    - ProductOrganizationRole
    - QuantityRange
    - ResponseCode
    - ScheduleTimeline
    - ScheduleTimelineExit
    - ScheduledInstance
    - Strength
    - Study
    - StudyAmendment
    - StudyAmendmentImpact
    - StudyAmendmentReason
    - StudyArm
    - StudyCell
    - StudyChange
    - StudyDefinitionDocument
    - StudyDefinitionDocumentVersion
    - StudyDesign
    - StudyElement
    - StudyEpoch
    - StudyIntervention
    - StudyRole
    - StudySite
    - StudyTitle
    - StudyVersion
    - SubjectEnrollment
    - Substance
    - SyntaxTemplate
    - SyntaxTemplateDictionary
    - Timing
    - TransitionRule
    range: string
    required: true
  name:
    name: name
    description: The literal identifier (i.e., distinctive designation) of the characteristic.
    title: Characteristic Name
    from_schema: https://example.org/usdm/v4/linkml
    exact_mappings:
    - ncit:C207477
    alias: name
    owner: IntercurrentEvent
    domain_of:
    - Activity
    - AdministrableProduct
    - AdministrableProductProperty
    - Administration
    - AnalysisPopulation
    - AssignedPerson
    - BiomedicalConcept
    - BiomedicalConceptCategory
    - BiomedicalConceptProperty
    - BiomedicalConceptSurrogate
    - BiospecimenRetention
    - EligibilityCriterion
    - Encounter
    - Estimand
    - GovernanceDate
    - Indication
    - MedicalDevice
    - NarrativeContent
    - NarrativeContentItem
    - Organization
    - PopulationDefinition
    - Procedure
    - ProductOrganizationRole
    - ResponseCode
    - ScheduleTimeline
    - ScheduledInstance
    - Strength
    - Study
    - StudyAmendment
    - StudyArm
    - StudyChange
    - StudyDefinitionDocument
    - StudyDesign
    - StudyElement
    - StudyEpoch
    - StudyIntervention
    - StudyRole
    - StudySite
    - SubjectEnrollment
    - Substance
    - SyntaxTemplate
    - SyntaxTemplateDictionary
    - Timing
    - TransitionRule
    range: string
    required: true
  label:
    name: label
    description: The short descriptive designation for the characteristic.
    title: Characteristic Label
    from_schema: https://example.org/usdm/v4/linkml
    exact_mappings:
    - ncit:C207476
    alias: label
    owner: IntercurrentEvent
    domain_of:
    - Activity
    - AdministrableProduct
    - Administration
    - AnalysisPopulation
    - AssignedPerson
    - BiomedicalConcept
    - BiomedicalConceptCategory
    - BiomedicalConceptProperty
    - BiomedicalConceptSurrogate
    - BiospecimenRetention
    - EligibilityCriterion
    - Encounter
    - Estimand
    - GovernanceDate
    - Indication
    - MedicalDevice
    - Organization
    - PopulationDefinition
    - Procedure
    - ProductOrganizationRole
    - ResponseCode
    - ScheduleTimeline
    - ScheduledInstance
    - Strength
    - Study
    - StudyAmendment
    - StudyArm
    - StudyChange
    - StudyDefinitionDocument
    - StudyDesign
    - StudyElement
    - StudyEpoch
    - StudyIntervention
    - StudyRole
    - StudySite
    - SubjectEnrollment
    - Substance
    - SyntaxTemplate
    - SyntaxTemplateDictionary
    - Timing
    - TransitionRule
    range: string
    required: false
  description:
    name: description
    description: A narrative representation of the characteristic.
    title: Characteristic Description
    from_schema: https://example.org/usdm/v4/linkml
    exact_mappings:
    - ncit:C207475
    alias: description
    owner: IntercurrentEvent
    domain_of:
    - Activity
    - AdministrableProduct
    - Administration
    - AnalysisPopulation
    - AssignedPerson
    - BiomedicalConceptCategory
    - BiomedicalConceptSurrogate
    - BiospecimenRetention
    - EligibilityCriterion
    - Encounter
    - Estimand
    - GovernanceDate
    - Indication
    - MedicalDevice
    - PopulationDefinition
    - Procedure
    - ProductOrganizationRole
    - ScheduleTimeline
    - ScheduledInstance
    - Strength
    - Study
    - StudyAmendment
    - StudyArm
    - StudyChange
    - StudyDefinitionDocument
    - StudyDesign
    - StudyElement
    - StudyEpoch
    - StudyIntervention
    - StudyRole
    - StudySite
    - SubjectEnrollment
    - Substance
    - SyntaxTemplate
    - SyntaxTemplateDictionary
    - Timing
    - TransitionRule
    range: string
    required: false
  text:
    name: text
    description: An instance of structured text that represents the characteristic.
    title: Characteristic Text
    from_schema: https://example.org/usdm/v4/linkml
    exact_mappings:
    - ncit:C207478
    alias: text
    owner: IntercurrentEvent
    domain_of:
    - Address
    - AdministrableProductProperty
    - AnalysisPopulation
    - CommentAnnotation
    - Duration
    - Identifier
    - Masking
    - NarrativeContentItem
    - PersonName
    - StudyAmendmentImpact
    - StudyTitle
    - SyntaxTemplate
    - TransitionRule
    range: string
    required: true
  notes:
    name: notes
    description: A brief written record relevant to the characteristic.
    title: Characteristic Notes
    from_schema: https://example.org/usdm/v4/linkml
    exact_mappings:
    - ncit:C215548
    alias: notes
    owner: IntercurrentEvent
    domain_of:
    - Abbreviation
    - Activity
    - AdministrableProduct
    - Administration
    - AnalysisPopulation
    - BiomedicalConcept
    - BiomedicalConceptCategory
    - BiomedicalConceptProperty
    - BiomedicalConceptSurrogate
    - EligibilityCriterion
    - Encounter
    - Estimand
    - Indication
    - MedicalDevice
    - PopulationDefinition
    - Procedure
    - StudyAmendment
    - StudyAmendmentImpact
    - StudyArm
    - StudyDefinitionDocument
    - StudyDefinitionDocumentVersion
    - StudyDesign
    - StudyElement
    - StudyEpoch
    - StudyIntervention
    - StudyRole
    - StudyVersion
    - SyntaxTemplate
    range: CommentAnnotation
    required: false
    multivalued: true
    inlined: true
    inlined_as_list: true
  dictionaryId:
    name: dictionaryId
    description: A USDM relationship between the Characteristic and SyntaxTemplateDictionary
      classes which provides the set of dictionary entries related to characteristics.
    from_schema: https://example.org/usdm/v4/linkml
    rank: 1000
    alias: dictionaryId
    owner: IntercurrentEvent
    domain_of:
    - SyntaxTemplate
    range: SyntaxTemplateDictionary
    required: false
    inlined: false
class_uri: usdm:IntercurrentEvent